As anxiety rates rise globally, researchers are turning to the gut for answers—and finding them in unexpected places. A new study has identified a promising probiotic strain, Limosilactobacillus reuteri WLR01 (GOLDGUT-LR99), with the potential to alleviate both anxiety-like behavior and gastrointestinal symptoms triggered by chronic stress.

By studying 11 strains of Lm. reuteri from healthy individuals, scientists found that WLR01 and WLR06 significantly improved symptoms in stressed mice—restoring cognitive function, reducing inflammation, and improving gut microbiota balance.

What’s especially exciting? WLR01 regulates key inflammation pathways (like NLRP3 inflammasome) and protects gut integrity in stress-induced models—offering insight into how targeted probiotics can impact both the brain and digestive system.

Unlike generic probiotics, the effects of L. reuteri are strain-specific—some are potent mood modulators, while others show no effect. WLR01 stands out for its dual action, and this study lays the groundwork for future clinical applications in treating anxiety and gut disorders—naturally, and without the side effects of traditional drugs.

For more information about topic, you can view the online video entitled "Limosilactobacillus reuteri Reduces Anxiety and Gut Symptoms in Stressed Mice".